Background and Objectives: To establish a simple and reproducible High Performance Liquid
Chromatography (HPLC) method for the determination of mizoribine in human plasma using glipizide
as Internal Standard (IS).
Methods: The mizoribine in plasma was precipitated with 10% perchloric acid and separated on a Phenomenex
Luna NH2 (250 mm
Keywords: Mizoribine, HPLC, therapeutic drug monitoring, clinical, application, validation.
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