Background: Xanthenes are a class natural and synthetic heterocyclic compounds that exhibit a
broad spectrum of biological and synthetic applications. The readership of this review paper will consist of
chemists involved with organic chemistry, synthetic organic chemists, pharmacists and biochemists.
Objective: This review aims to present an overview of the chemical aspects of low molecular weight xanthenes
and their chemical synthesis by cycloaddition in the search for bioactive species, new catalysts and other applications.
Method: We have comprehensively and critically discussed all the information available in the literature concerning
the synthesis and reactivity of this molecules.
Results: This manuscript presents an overview about the chemical aspects of low molecular weight xanthenes
and its chemical synthesis by cycloaddition in the search for bioactive species, new catalyst and other applications.
Conclusion: In summary, xanthenes are a class very explored because the broad spectrum of biological properties
as previously mentioned. Due this fact, synthetic strategies for obtain this system have been explored with
general success with two or three component, and for instance, with benzyne intermediates. It's possible react a
1,3-dicarbobyl compound such as lawsone, dimedone, Meldrum acid, coumarin, phenols and naphthols with