Advances in Physicochemical Properties of Biopolymers (Part 2)

Advances in Physicochemical Properties of Biopolymers (Part 2)

There is considerable diversity in polymers extracted from natural sources and much work has been done to classify them according to their physical and chemical properties. In the second part of ...
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Approaches for Improving the Mechanical Properties of Collagen Biomaterials

Pp. 354-370 (17)

María Victoria Tuttolomondo, Maria Lucia Foglia, Juan Manuel Galdopórpora and Martin Federico Desimone

Abstract

Collagen is a natural constituent of the extracellular matrix of tissues. It is well known that, when prepared without additives, diluted collagen hydrogels present poor mechanical properties limiting their use in tissue engineering. Hence, collagen's structural properties need to be enhanced. For this purpose, this chapter presents an overview of the recent advances and alternatives developed to improve the mechanical properties of collagen biomaterials.

Keywords:

Biomaterial, Collagen, Crosslink, Fibrils, Hydrogel, Mechanical properties, Thermal stability, Tissue engineering, Wound healing.

Affiliation:

IQUIMEFA-CONICET, Universidad de Buenos Aires, Facultad de Farmacia y Bioquímica, Cátedra de Química Analítica Instrumental. (1113) Junin 956 Piso 3. Ciudad de Buenos Aires, Argentina.