Title:The Bifidobacterim bifidum (BIB2) Probiotic Increased Immune System Factors in Men Sprint Athletes
VOLUME: 13
Author(s):Ali Hoseinkhani, Seyed Milad Mousavi Jazayeri, Elahe Ebrahimi, Elham Younesi-Melerdi and Ayoub Farhadi*
Affiliation:Department of Cellular and Molecular Biology, Young Researchers and Elite Club, Central Tehran Branch, Islamic Azad University, Tehran, Department of Microbiology, Science and Research Branch, Islamic Azad University, Guilan, Department of Microbiology, Pharmaceutical Sciences Branch, Islamic Azad University, Tehran, Genetics & Agricultural Biotechnology Institute of Tabarestan, Sari Agricultural Sciences and Natural Resources University, Sari, Laboratory for Molecular Cytogenetic, Faculty of Animal Sciences and Fisheries, Sari Agricultural Sciences and Natural Resources University, Sari
Keywords:Probiotics; CD4; IgA; IgM; Monocyte; Lymphocyte; Sprint athletes; Bifidobactrium bifidum (BIB2)
Abstract:Background: The probiotics supplemented foods enhance athletes’
immune system functions, improve body health and consequently decreases athletes health maintenance costs. Probiotics improve immune system functions against pathogens via affecting on innate immune system, humeral immunity and cytokines.
Objective: In this research, the effects of consumption of Iranian probiotic Bifidobactrium bifidum (BIB2) on athletes’ immune system functions were evaluated.
Methods: For this end, 56 men sprint athletes aged between 18 to 22 years with weights of 78 ± 5 kg were divided in two groups, one of them received fruit juice supplemented with Bifidobactrium bifidum (BIB2) probiotic and the other group had only fruit juice as control. Blood samples were collected from athletes after fasting, then once a month 24 h after 100 meters running and Immunoglobulin A (IgA), Immunoglobulin M (IgM), monocytes, lymphocytes and CD4 (T-helper cells) positive cells count were measured by ELISA kit, cell counter and flow cytometry, respectively.
Results: The obtained results showed significant differences between test and control groups, so that IgA, IgM, lymphocyte and monocytes percentage and CD4 measurements of test group were higher than control.
Conclusion: The Bifidobacterim bifidum (BIB2) probiotics consumption affected immune system and improved general health via increasing immune system factors.
