Background: Studies of phytochemicals, antioxidant vitamins and minerals in foods have
shown that the chemical compounds in foods are effective in the prevention or treatment of cancer and
other diseases. Alternative cancer treatments have also been tried by many cancer patients treated with
conventional therapies. Amygdalin therapy is used in many alternative treatments and has been
claimed to be effective. The aim of this review is to evaluate the studies that examine the reliability
and the efficacy of amygdalin use in the protocol for cancer patients.
Methods: All the studies related to amygdalin found by a search with the keywords, amygdalin, leatrile
and cancer. in databases such as PubMed, Google Scholar, Embase, ScienceDirect and BioMed
between 1975-2017 were examined.
Results: Two epidemiological studies, two case reports, three animal studies and five in vitro studies
were obtained by the search. In epidemiological studies and case reports, amygdalin was not determined
to have positive effects on cancer treatment. While one of the animal studies found a positive
effect, no positive effects were detected by the other two. In vitro studies have shown that amygdalin
has protective effects in the treatment of cancer.
Conclusion: This review concluded that there is no convincing evidence that amygdalin has positive
effects on cancer patients.