Apoptosis and Anti-cancer Drug Discovery: The Power of Medicinal Fungi and Plants

Author(s): Jack Ho Wong*, Stephen Cho Wing Sze*, Tzi Bun Ng*, Randy Chi Fai Cheung, Chit Tam*, Kalin Yanbo Zhang*, Xiuli Dan, Yau Sang Chan, William Chi Shing Cho, Charlene Cheuk Wing Ng, Mary Miu Yee Waye, Weicheng Liang, Jinfang Zhang, Jie Yang, Xiuyun Ye, Juan Lin, Xiujuan Ye*, Hexiang Wang, Fang Liu, David Wai Chan*, Hextan Yuen Sheung Ngan*, Ou Sha*, Guohui Li, Ryan Tse, Tak Fu Tse*, Helen Chan*.

Journal Name: Current Medicinal Chemistry

Volume 25 , Issue 40 , 2018

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Abstract:

The purpose of this account is to review the compounds capable of eliciting mitochondria-mediated apoptosis in cancer cells produced by medicinal fungi and plants. The medicinal fungi discussed encompass Cordyceps, Ganoderma species, Coriolus versicolor and Hypsizygus marmoreus. The medicinal plants discussed comprise Astragalus complanatus, Dendrobium spp, Dioscorea spp, Glycyrrhiza spp, Panax notoginseng, Panax ginseng, and Momordica charantia. These compounds have the potential of development into anticancer drugs.

Keywords: Medicinal fungi, medicinal plants, anticancer, apoptosis, mitochondria.

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Article Details

VOLUME: 25
ISSUE: 40
Year: 2018
Page: [5613 - 5630]
Pages: 18
DOI: 10.2174/0929867324666170720165005
Price: $58

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