Abstract
This review article provides an overview of hybrid and nanocomposite materials used as biomaterials in nanomedicine, focusing on applications in controlled drug delivery, tissue engineering, biosensors and theranostic systems. Special emphasis is placed on the importance of tuning the properties of nanocomposites, which can be achieved by choosing appropriate synthetic methods and seeking synergy among different types of materials, particularly exploiting their nanoscale nature. The challenges in fabrication for the nanocomposites are highlighted by classifying them as those comprising solely inorganic phases (inorganic/inorganic hybrids), organic phases (organic/organic hybrids) and both types of phases (organic/inorganic hybrids). A variety of examples are given for applications from the recent literature, from which one may infer that significant developments for effective use of hybrid materials require a delicate balance among structure, biocompatibility, and stability.
Keywords: Hybrid materials, nanocomposites, multifunctional biomaterials, theranostic systems, drug delivery systems, inorganic hybrids.
Current Pharmaceutical Design
Title:Hybrid Materials and Nanocomposites as Multifunctional Biomaterials
Volume: 23 Issue: 26
Author(s): Heveline D. M. Follmann, Alliny F. Naves, Rafael A. Araujo, Viktor Dubovoy, Xiaoxi Huang, Tewodros Asefa, Rafael Silva and Osvaldo N. Oliveira *
Affiliation:
- Sao Carlos Institute of Physics, University of Sao Paulo (USP) - PO Box 369, CEP 13566-590, Sao Carlos, Sao Paulo,Brazil
Keywords: Hybrid materials, nanocomposites, multifunctional biomaterials, theranostic systems, drug delivery systems, inorganic hybrids.
Abstract: This review article provides an overview of hybrid and nanocomposite materials used as biomaterials in nanomedicine, focusing on applications in controlled drug delivery, tissue engineering, biosensors and theranostic systems. Special emphasis is placed on the importance of tuning the properties of nanocomposites, which can be achieved by choosing appropriate synthetic methods and seeking synergy among different types of materials, particularly exploiting their nanoscale nature. The challenges in fabrication for the nanocomposites are highlighted by classifying them as those comprising solely inorganic phases (inorganic/inorganic hybrids), organic phases (organic/organic hybrids) and both types of phases (organic/inorganic hybrids). A variety of examples are given for applications from the recent literature, from which one may infer that significant developments for effective use of hybrid materials require a delicate balance among structure, biocompatibility, and stability.
Export Options
About this article
Cite this article as:
Follmann D. M. Heveline, Naves F. Alliny, Araujo A. Rafael , Dubovoy Viktor , Huang Xiaoxi , Asefa Tewodros , Silva Rafael and Oliveira N. Osvaldo*, Hybrid Materials and Nanocomposites as Multifunctional Biomaterials, Current Pharmaceutical Design 2017; 23 (26) . https://dx.doi.org/10.2174/1381612823666170710160615
DOI https://dx.doi.org/10.2174/1381612823666170710160615 |
Print ISSN 1381-6128 |
Publisher Name Bentham Science Publisher |
Online ISSN 1873-4286 |
Call for Papers in Thematic Issues
"Tuberculosis Prevention, Diagnosis and Drug Discovery"
The Nobel Prize-winning discoveries of Mycobacterium tuberculosis and streptomycin have enabled an appropriate diagnosis and an effective treatment of tuberculosis (TB). Since then, many newer diagnosis methods and drugs have been saving millions of lives. Despite advances in the past, TB is still a leading cause of infectious disease mortality ...read more
Current Pharmaceutical challenges in the treatment and diagnosis of neurological dysfunctions
Neurological dysfunctions (MND, ALS, MS, PD, AD, HD, ALS, Autism, OCD etc..) present significant challenges in both diagnosis and treatment, often necessitating innovative approaches and therapeutic interventions. This thematic issue aims to explore the current pharmaceutical landscape surrounding neurological disorders, shedding light on the challenges faced by researchers, clinicians, and ...read more
Emerging and re-emerging diseases
Faced with a possible endemic situation of COVID-19, the world has experienced two important phenomena, the emergence of new infectious diseases and/or the resurgence of previously eradicated infectious diseases. Furthermore, the geographic distribution of such diseases has also undergone changes. This context, in turn, may have a strong relationship with ...read more
Melanoma and Non-Melanoma Skin Cancer Treatment: Standard of Care and Recent Advances
In this thematic issue, we aim to provide a standard of care of the diagnosis and treatment of melanoma and non-melanoma skin cancer. The editor will invite authors from different countries who will write review articles of melanoma and non-melanoma skin cancers. The Diagnosis, Staging, Surgical Treatment, Non-Surgical Treatment all ...read more
- Author Guidelines
- Graphical Abstracts
- Fabricating and Stating False Information
- Research Misconduct
- Post Publication Discussions and Corrections
- Publishing Ethics and Rectitude
- Increase Visibility of Your Article
- Archiving Policies
- Peer Review Workflow
- Order Your Article Before Print
- Promote Your Article
- Manuscript Transfer Facility
- Editorial Policies
- Allegations from Whistleblowers
- Announcements