Abstract
Background: Polysaccharides are widely found in animals, plants and micro- organisms, and are closely related to various physiological functions. It is one of the four basic substances that constitute life activities. Polysaccharide has antitumor, antivirus, antioxidant, immune regulation and other biological activities.
Objective: Because the polysaccharide has significant antitumor effect and small side-effects, it has become the focus of the current antitumor drug research.
Results: Herein, the polysaccharide species with antitumor effect were summarized in recent years, and the antitumor activity mechanisms of polysaccharides were analyzed and discussed.
Conclusion: Many polysaccharides have good antitumor activity, and they have broad application prospects.
Keywords: Polysaccharides, antitumor, biological activities, mechanisms, discuss, summarize.
Current Drug Targets
Title:Antitumor Activity of Polysaccharides: An Overview
Volume: 19 Issue: 1
Author(s): Ling Chen and Gangliang Huang*
Affiliation:
- Active Carbohydrate Research Center, College of Chemistry, Chongqing Normal University, Chongqing, 401331,China
Keywords: Polysaccharides, antitumor, biological activities, mechanisms, discuss, summarize.
Abstract: Background: Polysaccharides are widely found in animals, plants and micro- organisms, and are closely related to various physiological functions. It is one of the four basic substances that constitute life activities. Polysaccharide has antitumor, antivirus, antioxidant, immune regulation and other biological activities.
Objective: Because the polysaccharide has significant antitumor effect and small side-effects, it has become the focus of the current antitumor drug research.
Results: Herein, the polysaccharide species with antitumor effect were summarized in recent years, and the antitumor activity mechanisms of polysaccharides were analyzed and discussed.
Conclusion: Many polysaccharides have good antitumor activity, and they have broad application prospects.
Export Options
About this article
Cite this article as:
Chen Ling and Huang Gangliang *, Antitumor Activity of Polysaccharides: An Overview, Current Drug Targets 2018; 19 (1) . https://dx.doi.org/10.2174/1389450118666170704143018
DOI https://dx.doi.org/10.2174/1389450118666170704143018 |
Print ISSN 1389-4501 |
Publisher Name Bentham Science Publisher |
Online ISSN 1873-5592 |
Call for Papers in Thematic Issues
New drug therapy for eye diseases
Eyesight is one of the most critical senses, accounting for over 80% of our perceptions. Our quality of life might be significantly affected by eye disease, including glaucoma, diabetic retinopathy, dry eye, etc. Although the development of microinvasive ocular surgery reduces surgical complications and improves overall outcomes, medication therapy is ...read more
- Author Guidelines
- Graphical Abstracts
- Fabricating and Stating False Information
- Research Misconduct
- Post Publication Discussions and Corrections
- Publishing Ethics and Rectitude
- Increase Visibility of Your Article
- Archiving Policies
- Peer Review Workflow
- Order Your Article Before Print
- Promote Your Article
- Manuscript Transfer Facility
- Editorial Policies
- Allegations from Whistleblowers
Related Articles
-
Using Protein-protein Interaction Network Information to Predict the Subcellular Locations of Proteins in Budding Yeast
Protein & Peptide Letters Probiotics and the Intestinal Microflora: What Impact on the Immune System, Infections and Aging?
Current Nutrition & Food Science Preparation and Primary Bioevaluation of 99mTc-labeled-1-thio-β-D-Glucose as Melanoma Targeting Agent
Current Radiopharmaceuticals Emerging Drugs for the Treatment of Breast Cancer Brain Metastasis: A Review of Patent Literature
Recent Patents on Anti-Cancer Drug Discovery Synthesis, Evaluation of Biological Activity, Docking and Molecular Dynamic Studies of Pyrimidine Derivatives
Letters in Organic Chemistry Retinal Degenerations: From Cell Signaling to Cell Therapy; Pre-Clinical and Clinical Issues
Current Gene Therapy Flexible Estrogen Receptor Modulators: Synthesis, Biochemistry and Molecular Modeling Studies for 3-Benzyl-4,6-diarylhex-3-ene and 3,4,6-Triarylhex-3-ene Derivatives
Medicinal Chemistry “Self-Antigenic Universe” and Tuberculosis Vaccine Development
Current Pharmacogenomics and Personalized Medicine Pharmacogenomics of Human ABC Transporter ABCC11 (MRP8): Potential Risk of Breast Cancer and Chemotherapy Failure
Anti-Cancer Agents in Medicinal Chemistry Synthesis and Stereochemistry-Activity Relationship of Chiral Thiourea Derivatives as Potential Anticancer Agents
Anti-Cancer Agents in Medicinal Chemistry Evaluation of <sup>177</sup>Lu-EDTMP in Dogs with Spontaneous Tumor Involving Bone: Pharmacokinetics, Dosimetry and Therapeutic Efficacy
Current Radiopharmaceuticals Hemichannels in the Neurovascular Unit and White Matter Under Normal and Inflamed Conditions
CNS & Neurological Disorders - Drug Targets Metabolomic and Imaging: A Literature Review
Current Medical Imaging The Leukocyte Common Antigen-Related Protein LAR: Candidate PTP for Inhibitory Targeting
Current Topics in Medicinal Chemistry Synthesis and Antiproliferative Activity of New Coumarin-Based Benzopyranone Derivatives Against Human Tumor Cell Lines
Medicinal Chemistry Farnesyltransferase Inhibitors: A Detailed Chemical View on an Elusive Biological Problem
Current Medicinal Chemistry Candida Infections and Human Defensins
Protein & Peptide Letters Cytoskeletal Alterations that Confer Resistance to Anti-tubulin Chemotherapeutics
Anti-Cancer Agents in Medicinal Chemistry Terpenes with Antitumor Activity: A Patent Review
Recent Patents on Anti-Cancer Drug Discovery Cancer Drug Development with the Help of Radiopharmaceuticals: Academic Experience
Current Pharmaceutical Design