Background and Objective: In a security ward we assessed the diagnostic contribution
of single photon scintigraphy [SPECT] in our diagnostic pathway for patients with serious mental
disease and a history of violence.
Methods: Twenty patients were examined between 2012 and 2015 and the findings compared to
those in nine patients with the same diagnosis, but no history of violence.
Results: All violent patients had areas with reduced accumulation of 99
mTc-HMPAO frontally and
in the temporal lobe, in the non-violent group only two patients demonstrated these findings.
Conclusion: Traditionally, low accumulation of the tracer in SPECT is related to reduced perfusion
of brain tissue. We discuss our findings in the light of other possible pathophysiological