Background: Phytosterols is a steroidal compound having similar structure of
cholesterol and more than 200 different types of sterols have been separated and isolated
from different plants. Phytosterols are basically used as food supplements which are having
Objective: Phytosterols are available in the market in the form of capsules and tablets with
other multivitamins. Average intake of naturally occurring phytosterols ranges between 150-
450 mg/day. β-sitosterol is one of the natural occuring phytosterols having steroidal moiety.
β-sitosterol reduces cholesterol levels by competing with cholesterol for absorption in the
intestine, and due to these aspects, it is valuable for cardiovascular protection. β-sitosterol
also inhibits tumor growth, modulates immune response and has antioxidant capacity. In the
future, β-sitosterol could be a potential chemo preventive agent for the treatment of various
types of cancer including prostatic carcinoma and breast cancer.
Conclusion: In the present paper, we collected the data regarding detailed pharmacological
activities and analytical aspects of β -sitosterol which will be beneficial to the researchers,
scientist and other persons of medical and pharmaceutical field.