Intramolecular Cyclization of N-Arylpropiolamides: A New Strategy for the Synthesis of Functionalized 2-Quinolones

Author(s): Esmail Vessally , Mirzaagha Babazadeh* , Khadijeh Didehban , Akram Hosseinian , Ladan Edjlali .

Journal Name: Current Organic Chemistry

Volume 21 , Issue 25 , 2017

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Abstract:

This review article is an attempt to highlight the most important contributions toward the synthesis of functionalized 2-quinolone derivatives from cyclization of N-arylpropiolamides with the emphasis on the mechanistic aspects of the reactions.

Keywords: N-arylpropiolamides, 2-quinolones, electrophilic cyclization, hydroarylation, Ullmann C-N coupling, palladium.

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Article Details

VOLUME: 21
ISSUE: 25
Year: 2017
Page: [2561 - 2572]
Pages: 12
DOI: 10.2174/1875692115666170612103356
Price: $58

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