Introduction: Although Raynaud's Phenomenon (RP) is observed in a significant proportion
of patients with primary fibromyalgia, the available data on capillaroscopic findings in primary
fibromyalgia are scarce.
Objective: The purpose of the study was to assess the capillaroscopic pattern in patients with primary
Patients and Methods: 26 patients with primary fibromyalgia (25 women and 1 man) were included
in the study. Mean age was 55±10 years. As control groups were examined 31 patients with
primary RP and 35 healthy volunteers. Capillaroscopic examination was performed with a videocapillaroscope
Videocap 3.0 (DS Medica), magnification 200x with analysis of the main capillaroscopic
parameters as follows: capillary distribution, shape, mean capillary diameters and length,
mean capillary density, visibility of the subpapillary plexus; presence of avascular areas, microhaemorrhages
and neoangiogenic capillaries.
Results: Symptoms of RP were observed in 65% (17/26) of the cases with primary fibromyalgia.
At capillaroscopic examination, the most frequent finding in patients with primary fibromyalgia
was the presence of capillary dilation in 85% (22/26) of the patients - both in cases with and without
RP. However, the mean arterial and venous capillary diameters were significantly higher in the
subgroup of fibromyalgia patients with clinical symptoms of RP. Of note, microvascular abnormalities
characteristic of connective tissue diseases could not be observed in primary fibromyalgia
patients. Analogous changes - presence of dilated capillaries - were found in 96.6% (29/30) of patients
with primary RP.
Conclusion: In our study, the most frequent capillaroscopic finding in patients with primary fibromyalgia
was the presence of dilated capillary loops analogous to primary RP. Capillaroscopic
signs suggestive of connective tissue disease could not be found in primary fibromyalgia patients.