Background: More than a century ago, Paul Ehrlich proposed the idea of a
drug working as a “magic bullet” that selectively eliminates diseased cells without harming
the surrounding normal cells. Since then, much progress has been made in this field to
broaden the scope for targeted delivery of drugs. A major problem remain the toxic effects
of targeted drugs on healthy cells. In order to reduce the adverse effects of chemotherapy
on healthy tissues, we survey the use of recent drug delivery systems for targeted therapy.
Objective: The selective delivery of the drugs to specific diseased cells or tissues still is a
daunting task. Ideally, for target drug delivery systems, the system should be made up of
carriers and drugs, where carriers precisely target the desired drug. This issue covers the
recent advancements in modern techniques for such purposes.
Result and Conclusion: It encompasses advances, benefits and limitations in state of art
work of targeted drug delivery through hydrogels, microfluidics, nanoparticles, carbon
nanotubes, polymeric micelles, liposomes, lipoprotein based drug carriers and dendrites.