Fast Dissolving/Disintegrating Dosage Forms: Introducing through Development, Market, Pharmacopoeial and Regulatory Status
Pp. 3-18 (16)
Vikas A. Saharan, Anupama Singh and Vandana Kharb
Fast Dissolving/Disintegrating Dosage Forms (FDDFs) have emerged as
alternate dosage forms for patients who cannot swallow or who should not swallow or
who refuse to swallow conventional tablets/capsules and liquid formulations. FDDFs
include Fast Dissolving/Disintegrating Tablets (FDTs), Fast Dissolving/Disintegrating
Oral Films (FDOFs), Fast Dissolving/Disintegrating Capsules (FDCs), Fast
Dissolving/Disintegrating Pellets (FDPs), etc. These dosage forms dissolve/disintegrate
quickly, when placed on tongue, resulting in solution/suspension, which can be
swallowed easily and hence do not require water for their oral ingestion. This chapter
introduces FDDFs rationale, their brief history, regulatory/pharmacopoeial aspects,
advantages/disadvantages and their market potential.
Absorption, Capsule, Dysphagia, FDT, Film, Freeze drying, Geriatric,
Granule, Mini tablet, Nausea, ODT, Orodispersible, Paediatric, Parkinsonism,
Pellet, Pharmacopoeia, Psychotic, Quality of life, Tablet, Travellers.
Department of Pharmaceutics, School of Pharmaceutical Sciences, Sardar Bhagwan Singh Post Graduate Institute of Biomedical Sciences and Research (www.sbspgi.edu.in), Balawala, Dehradun 248161, Uttarakhand, India.