Cancer Preventive and Therapeutic Compounds: Gift From Mother Nature

Cancer is a major cause of deaths all around the globe. Although numerous anticancer drugs are available, most of them are expensive and have serious side effects. Natural compounds are usually ...
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Marine Natural Products for Cancer Prevention and Therapy: A Mechanistic Overview

Pp. 125-146 (22)

Shankar Suman, Sanjay Mishra and Yogeshwer Shukla

Abstract

Marine resources have rich pharmaceutical values as they encompass a diverse taxonomy of biological species and possess a large-scale of bioactive compounds. The existence of extraordinary chemical diversity of marine resources is used to discover anticancer agent in its natural or derived synthetic form. Marine flora and fauna possess several valuable compounds with immunostimulatory and antioxidant properties, also gained their importance as nutraceuticals as well as in cancer chemoprevention. In this chapter, we have emphasized for overviewing the marine natural products; those having anticancer or cancer chemo-preventive properties, acting against different deregulated cellular and molecular pathways associated with cancer development or progression.

Keywords:

Cancer, Cell signaling pathways, Flora, Fauna, Marine compounds.

Affiliation:

Proteomics and Environmental Carcinogenesis Laboratory, CSIR-Indian Institute of Toxicology Research, M.G. Marg, Lucknow, India.