Background: SnCl2·2H2O has been used as a convenient precatalyst for the one-pot and
rapid synthesis of 2-substituted quinolines under ultrasound irradiation in water. The reaction involved
a 3-component reaction of aniline, aldehydes, and ethyl 3,3-diethoxypropionate in the presence of aerial
oxygen to give the desired products in good yields.
Conclusion: Several of these compounds showed antibacterial activities when tested against gram-positive
and gram-negative species. One compound i.e. 4b showed promising activities across both the species.
Keywords: Antibacterial, MCRs, quinoline, ultrasound, water, SnCl2.
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