Ultrasound assisted synthesis of quinoline derivatives in the presence of SnCl2•2H2O as a precatalyst in water: evaluation of their antibacterial activities (E-pub Abstract Ahead of Print)
A. S. G. Prasad,
T. Bhaskara Rao,
Mandava V. Basaveswara Rao,
SnCl2•2H2O has been used as a convenient precatalyst for the one-pot and rapid synthesis of 2-substituted quinolines under ultrasound irradiation in water. The reaction involved a 3-component reaction of aniline, aldehydes and ethyl 3,3-diethoxypropionate in the presence of aerial oxygen to give the desired products in good yields. Several of these compounds showed antibacterial activities when tested against gram-positive and gram-negative species. One compound i.e. 4b showed promising activities across both the species.
Keywords: Quinoline, Ultrasound, Water, SnCl2
Rights & PermissionsPrintExport