Introduction: Piroxicam (PRX) is a widely consumed anti-inflammatory drug, and the assays
of its tablets and gels for quality control are mostly performed through High Performance Liquid Chromatography
with Ultraviolet Detector (HPLC-UV).
Methods: In this regard, an alternate approach, LaFeO3 nanoparticles-modified carbon paste electrode
was prepared in order to carry out PRX analysis by using voltammetric approaches.
Results: The modified electrode showed better analytical signal. The calibration curve is in the concentration
range of 9.00 and 180.00 µmol·L-1 and the limit of detection was obtained as 1.00 µmol·L1 for
PRX. The calculated recovery rate was fairly good (99.14%) in comparison with the declared value in
the commercial product.
Conclusion: As shown by the low overall process cost, performance quickness and analytical results,
the proposed method of electroanalysis with the LaFeO3 nanoparticles-modified carbon paste electrode
presents a viable and interesting alternative approach to identification and determination of PRX compound
in commercial products.