Nanoscale Functional Biomaterials for Cancer Theranostics

Author(s): Linying Liu, Xiaoshuang Li, Lei Chen*, Xin Zhang*.

Journal Name: Current Medicinal Chemistry

Volume 25 , Issue 25 , 2018

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Abstract:

Nanomedicine is widely developed in recent years. In nanomedicine system, nanoscale and nanostructured functional materials are used to manipulate the human biology systems at the molecular level for cancer imaging and therapy. New nanostructure based functional materials consist of nanoscale liposomes, spheres, micelles, capsules, emulsion, suspension and phamacosomes. Several functional nanoparticles such as lipidbased and polymer-based materials are demonstrated to be drug delivery vehicles and imaging agents. These materials are biodegradable, biocompatible and have better biodistribution, lower side effect and lower toxicity. In addition, hybrids with these materials coating provide uniquely electrical, optical and magnetic properties. This review discusses the research on the applications of functional materials, especially nanoparticles as imaging contrast agents, cancer therapeutic agents and multi-functional agents and this review focused on the theranostic integration treatments on liver cancer and brain cancer.

Keywords: Nanomaterials, biomaterials, cancer, imaging, therapy, theranostics, liver tumor, gliomatosis cerebri.

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Article Details

VOLUME: 25
ISSUE: 25
Year: 2018
Page: [2987 - 3000]
Pages: 14
DOI: 10.2174/0929867324666170406111036
Price: $58

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