Background: A series of novel substituted 3-(thiophen-2-yl)pyrazoles was synthesized
efficiently and in high yields using simple and convenient procedures starting from 1-phenyl-3-
Methods: The structures of the newly synthesized products were established and their antimicrobial
activities were investigated against some bacteria and fungi.
Results and Conclusion: The products showed excellent antimicrobial activities against the tested
microorganism compared to the standard antibacterial and antifungal drugs.
Keywords: Drug design, antimicrobial activity, microorganisms, 3-(thiophen-2-yl)pyrazoles, hydrazides, inhibition zone.
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