Role of Cartilage Regeneration in the Management of Early Knee Arthritis: Current Concepts
Pp. 70-90 (21)
Mark F. Sommerfeldt, Avijit Sharma and David C. Flanigan
In this chapter, we discuss review cartilage restoration surgery in the setting
of early knee osteoarthritis (OA). We introduce an algorithmic approach to
determining treatment and discuss procedures including microfracture, autologous
matrix-induced chondrogenesis (AMIC®), osteochondral autograft transfer (OATS),
osteochondral allografting (OCA), autologous chondrocyte implantation (ACI)/matrixassisted
chondrocyte implantation (MACI), and stem cell therapy. These techniques
have particular advantages and disadvantages. The authors share their approach and
outline the protocol for postoperative rehabilitation.
ACI, AMIC, Cartilage, MACI, Microfracture, OATS, OCA,
Osteoarthritis, Rehabilitation, Stem cell therapy.
OSU Sports Medicine and Cartilage Restoration Program, Department of Orthopaedics, The Ohio State University Wexner Medical Center, Columbus, Ohio, USA.