Plants, being sessile organisms, constantly withstand environmental fluctuations, including
low- temperature, also referred as cold stress. Whereas cold poses serious challenges at both physiological
and developmental levels to plants growing in tropical or sub-tropical regions, plants from
temperate climatic regions can withstand chilling or freezing temperatures . Several cold inducible
genes have already been isolated and used in transgenic approach to generate cold tolerant plants. The
conventional breeding methods and marker assisted selection have helped in developing plant with
improved cold tolerance, however, the development of freezing tolerant plants through cold acclimation
remains an unaccomplished task. Therefore, it is essential to have a clear understanding of how
low temperature sensing strategies and corresponding signal transduction act during cold acclimation
process. Herein, we synthesize the available information on the molecular mechanisms underlying
cold sensing and signaling with an aim that the summarized literature will help develop efficient
strategies to obtain cold tolerant plants.
Keywords: Cold, Calcium, Protein kinase, CBF, Signaling, Phosphorylation.
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