Topics in Neurology
Pp. 273-286 (14)
Over the last decade there have been many advances in neurology. This
article reviews topics in neurology, specifically for stroke and neurodegenerative
diseases. Advances in magnetic resonance imaging provide a powerful tool for
diagnosing stroke and thrombolysis by alteplase and have facilitated a paradigm shift in
the approach to super-acute phase ischemic stroke. Secondary prevention of ischemic
stroke has changed in terms of both anti-platelet therapy and anti-coagulation therapy.
Over the last decade, understanding about the etiology and pathogenesis of many
neurodegenerative diseases has progressed. Recent reports are reviewed here regarding
Alzheimer’s disease, Parkinson disease, dementia with Lewy bodies, motor neuron
disease and frontotemoral dementia as they share many common mechanisms involving
aggregation and accumulation of proteins.
Neurocognitive disorders, Neurodegenerative diseases, Novel oral
anticoagulation agents, Stroke, Thrombolysis.
Department of Neurology, National Hospital Organization, Kure Medical Center and Chugoku Cancer Center, 3-1 Aoyama-cho, Kure 737-0014, Japan.