Background: Variation in neonatal skin changes and clinical presentation is a frequent
occurrence. We studied the pattern of cutaneous manifestations in new-borns <72 hours of birth.
Method: We included all live babies delivered in our hospital; Babies were categorised according
to age, birth weight and gestational age. Neonates were examined within 24 hours of birth and daily
for skin lesions for 72 hours. Skin lesions were categorised into physiological, transient eruptions,
due to infections, congenital anomalies and miscellaneous.
Results: Of 200 new-borns, 108 (54%) were females; 180 (90%) full term babies (37-41 weeks).
Non-consanguinity was noted in parents of 175 (87.5%) babies. One hundred and thirty one (65%)
babies were delivered normally by vaginal route, and 69 (34.5%) by Caesarean section. 176
(88.0%) were average birth weight babies. Mean±SD lesion burden/neonate was 3.925±1.2 (n=785
lesions, 1-8 lesions/neonate). Transient skin lesions were frequent (n=451 in 198 patients,
Mean±SD 2.30±0.76) followed by physiological conditions (n=284, Mean±SD 1.44±0.82). Infectious,
developmental, iatrogenic and miscellaneous lesions were less frequent (mean±SD lesions
0.015±0.12, 0.0115±0.32, 0.015±0.12, and 0.035±0.18, respectively). Statistically significant
(p<0.001) relationship was noted between gestational age and number of lesions; more number of
full term babies had lesions, while number of lesions (>6) were more in preterm babies. All lesions
occurred within 24 hours of birth except erythema toxicum neonatorum (n=124) wherein 80 were
seen on day 1, and 43 on day 2.
Conclusion: We confirm the variation in cutaneous lesions and their time of onset in neonates.
Transient and physiological changes are more frequent and disappeared spontaneously. Number of
lesions/neonate was more in premature babies.