Objectives: Find possible causative agents causing cutaneous adverse reactions; clinical
patterns, causality and severity of Drug induced cutaneous adverse reactions (CADR) and treatment
Methods: Retrospective study was undertaken including cases of CADR. Causality, preventability and
severity of Drug Induced cutaneous reactions were judged with the use of Naranjo's algorithm, WHO
causality scale, modified Schumock and Thorton scale, and Hartwig’s scale respectively.
Results: Among 275 total cADRs reported, Antimicrobials (46.55%) were the main drugs involved
followed by Non steroidal anti-inflammatory drugs (NSAIDs) (25.09%) and Antifungal (9.82%).
Urticaria (63.64%) followed by Erythema multiform(12.36%) was most frequently observed CDRs.
Amongst all cADRs 50.18% were certain according to Naranjo’s scale, none of them were preventable
according to modified Schumock and Thorton scale. All reactions were moderate according to
Hartwig’s severity scale.
Conclusion: It was observed that antibiotics and NSAIDs cause maximum number of CADRs.
Therefore strict vigilance is required while using them.