Exploring 1,3,4-Oxadiazole Scaffold for Anti-inflammatory and Analgesic Activities: A Review of Literature From 2005-2016

Author(s): Gita Chawla*, Baby Naaz, Anees A. Siddiqui.

Journal Name: Mini-Reviews in Medicinal Chemistry

Volume 18 , Issue 3 , 2018

Become EABM
Become Reviewer

Graphical Abstract:


Abstract:

1,3,4-Oxadiazole derivatives are found to have a wide range of pharmacological activities and attracting the researchers to work on this nucleus. Literature survey indicates that many 1,3,4- oxadiazoles have been synthesized with the aim to get compounds of significant anti-inflammatory and analgesic activities with reduced adverse effects. The purpose of this review is to compile the reports on 1,3,4-oxadiazole derivatives possessing anti-inflammatory and analgesic activities. The review also includes the reports on 1,3,4-oxadiazole derivatives of existing NSAIDs in the last ten years.

Keywords: Analgesic, anti-inflammatory, scaffold, COX, 1, 3, 4-Oxadiazole, NSAIDs.

Rights & PermissionsPrintExport Cite as

Article Details

VOLUME: 18
ISSUE: 3
Year: 2018
Page: [216 - 233]
Pages: 18
DOI: 10.2174/1389557517666170127121215
Price: $58

Article Metrics

PDF: 25
HTML: 3
EPUB: 1
PRC: 1