Single-drop Microextraction and Related Techniques
Pp. 327-379 (53)
Francisco Pena-Pereira, Isela Lavilla and Carlos Bendicho
The number of applications of liquid phase microextraction (LPME)
techniques has undergone a dramatic increase during the last years. Miniaturisation of
sample preparation encompasses several advantages, i.e., low consumption of extractants,
integrated operation, ease of clean-up, large preconcentration factors, apart from
an increased greenness, as compared to classical solvent extraction. Among LPME,
single-drop microextration (SDME) approaches have deserved much interest. Versatile
and adaptable procedures to every each analyte and matrix have been reported.
Extractants are not only limited to organic solvents, but ionic liquids (ILs) and even
aqueous solvents can be also employed. Whereas, analytical techniques based on
chromatographic/electrophoretic separations and some modes of atomic spectrometry
were applied in early applications, SDME has also been exploited in combination with
other detection approaches such as UV-vis spectrophotometry, fluorospectrometry,
chemiluminescence, etc. This has spread the use of SDME to almost every application
area. In this chapter, the state of art of SDME and its main modes is reviewed.
Anions, Atomic-spectrometry, Continuous-flow, Direct-immersion,
Directly-suspended, Electrophoresis, Elements, Gas-chromatography, Headspace,
Ionic-liquids, Liquid-chromatography, Mass-spectrometry, Microextraction, Organic-
compounds, Organometals, Single-drop, Speciation, Three-phases, Traceanalysis,
Departamento de Química Analítica y Alimentaria, Área de Química Analítica, Facultad de Química, Universidad de Vigo, Campus As Lagoas-Marcosende s/n, 36310 Vigo, Spain.