Microextraction by Packed Sorbent (MEPS): Theory, Developments and Applications
Pp. 241-253 (13)
Mohammad Mahdi Moein, Abbi Abdel-Rehim and Mohamed Abdel-Rehim
Sample preparation is a critical issue in bioanalysis since the matrix is often
complex. A good sample preparation technique will remove the possible interferences
from the sample matrix pre-concentrate the analyte and to be reproducible independent
of the sample matrix. Recent developments of sample preparation techniques are
directed toward automation, the smaller sample volumes and online coupling of sample
preparation units and detection systems. Microextraction in packed syringe (MEPS) is a
new type of solid-phase extraction (SPE) technique that is miniaturized and can be
fully automated. In MEPS the solid bed is integrated in the injection syringe. The
MEPS syringe can be used online for both extraction and injection of samples. The
present chapter gives an overview of MEPS technique, including the MEPS
description, formats, sorbents, experimental and protocols and factors that affect the
MEPS performance. We also summarize MEPS recent applications in bioanalysis,
environmental and food analysis.
Applications, Experimental protocols, Microextraction by packed
sorbent (MEPS), Sorbents.
Department of Analytical Chemistry, Stockholm University, SE10691 Stockholm, Sweden.