Title:Treatment Avenues for Type 2 Diabetes and Current Perspectives on Adipokines
VOLUME: 14 ISSUE: 3
Author(s):Sayantani Pramanik, Nirali Rathwa, Roma Patel, A.V. Ramachandran and Rasheedunnisa Begum*
Affiliation:Department of Biochemistry, Faculty of Science, The Maharaja Sayajirao University of Baroda, Vadodara, Gujarat, Department of Biochemistry, Faculty of Science, The Maharaja Sayajirao University of Baroda, Vadodara, Gujarat, Department of Biochemistry, Faculty of Science, The Maharaja Sayajirao University of Baroda, Vadodara, Gujarat, Department of Zoology, Faculty of Science, The Maharaja Sayajirao University of Baroda, Vadodara, Gujarat, Department of Biochemistry, Faculty of Science, The Maharaja Sayajirao University of Baroda, Vadodara, Gujarat
Keywords:Type 2 diabetes, therapeutics, gut and brain derived molecules, adipokines, small molecule drugs, phytochemicals.
Abstract:Background: Diabetes has turned into a pandemic disorder that is affecting millions of people
worldwide. Industries are aggressively racing and pursuing research towards the discovery of antidiabetic
drug and the current global sale of such drugs are ever on the increase. However, in spite of
such massive level of expenditure thereof, WHO projects that by 2030, diabetes will rank as the 7th
leading cause of mortality.
Objective: It is in this context that we have reviewed here the various approaches available and possible
towards diabetes management. This review also includes the WHO guidelines for controlling the glycemic
levels, which must be known and followed by clinicians for a better diabetes management.
Conclusion: Despite having a wealth of FDA-approved therapeutic options for type 2 diabetes majorities
of the patients are not able to achieve the appropriate glycemic control due to various factors. The
development of new options with actions at multiple foci of diabetic manifestation and better efficacy
may potentially help in improving the current scenario of T2D management.
