Sumoylation in Lens Differentiation and Pathogenesis
D. W.-C. Li.
Sumoylation, a post-translational modification discovered over a
decade ago, turns out to be a very important regulatory mechanism
mediating multiple cellular processes. Recent studies from our laboratory
and others also revealed that it plays a crucial role in regulating both
differentiation and pathogenesis of the ocular lens. This review will
summarize these progresses.
Keywords: Lens, sumoylation, differentiation, cataractogenesis, pathogenesis.
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