Common Therapeutic Modalities Against Diabetes and Associated Cardiovascular Disease

Author(s): Nasimudeen R Jabir, Chelapram Kandy Firoz, Ghulam Md Ashraf, Syed Kashif Zaidi, Shazi Shakil, Mohammad Amjad Kamal, Shams Tabrez*.

Journal Name: Current Vascular Pharmacology

Volume 15 , Issue 4 , 2017

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Abstract:

Despite recent advances in medical research, the incidence of diabetes and cardiovascular disease (CVD)-induced fatal events is increasing. The literature point towards several co-occurring pathways that could lead to terminal complications related with these diseases. Different pathophysiological alterations such as hyperglycaemia, hyperinsulinaemia, insulin resistance, obesity, endothelial dysfunction and oxidative stress lead to the initiation and progression of atherosclerotic plaques. In view of the continuous rise in fatal events and overlapping pathological conditions associated with CVD and diabetes, there is a critical need to develop a common treatments against these diseases. The present review highlights the possible use of common drugs that could target diabetes and associated CVD.

Keywords: Cardiovascular disease, diabetes mellitus, glycaemic imbalance, obesity, oxidative stress.

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Article Details

VOLUME: 15
ISSUE: 4
Year: 2017
Page: [365 - 373]
Pages: 9
DOI: 10.2174/1570161115666170105125034
Price: $58

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