The employment of comet assay has gained wide importance in various areas
that focus on human bio-monitoring, genetic toxicology, molecular epidemiology and ecogenotoxicity.
Comet assay has become among the standard methods for evaluating genotoxicity
by the determination of DNA damage caused by mutagens, and this assay has been
extensively applied by the researchers for the past 20 years. This review discusses comet
assay, as well as its application in various fields.
Keywords: Bio-monitoring, comet assay, DNA damage, genotoxicity, mutagens, toxicology.
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