Aim of this article is to review and discuss the currently used quantitative
analytical method ICP-MS, which is used for quality control of pharmaceutical
products. ICP-MS technique has several applications such as determination of single
elements, multi element analysis in synthetic drugs, heavy metals in environmental
water, trace element content of selected fertilizers and dairy manures. ICP-MS is also
used for determination of toxic and essential elements in different varieties of food
samples and metal pollutant present in the environment. The pharmaceuticals may
generate impurities at various stages of development, transportation and storage
which make them risky to be administered. Thus, it is essential that these impurities
must be detected and quantified. ICP-MS plays an important function in the
recognition and revealing of elemental impurities.
Keywords: Elements, impurities, analytical techniques, ICP, MS, ICP-MS.
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