ICP-MS: Analytical Method for Identification and Detection of Elemental Impurities

Author(s): Mohini Mittal, Kapil Kumar, Durgadas Anghore, Ravindra K. Rawal*.

Journal Name: Current Drug Discovery Technologies

Volume 14 , Issue 2 , 2017

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Abstract:

Aim of this article is to review and discuss the currently used quantitative analytical method ICP-MS, which is used for quality control of pharmaceutical products. ICP-MS technique has several applications such as determination of single elements, multi element analysis in synthetic drugs, heavy metals in environmental water, trace element content of selected fertilizers and dairy manures. ICP-MS is also used for determination of toxic and essential elements in different varieties of food samples and metal pollutant present in the environment. The pharmaceuticals may generate impurities at various stages of development, transportation and storage which make them risky to be administered. Thus, it is essential that these impurities must be detected and quantified. ICP-MS plays an important function in the recognition and revealing of elemental impurities.

Keywords: Elements, impurities, analytical techniques, ICP, MS, ICP-MS.

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Article Details

VOLUME: 14
ISSUE: 2
Year: 2017
Page: [106 - 120]
Pages: 15
DOI: 10.2174/1570163813666161221141402
Price: $58

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