Structural, Functional and Evolutionary Aspects of Seed Globulins | BenthamScience


Structural, Functional and Evolutionary Aspects of Seed Globulins

Author(s): Pooja Kesari, Neetu, Anchal Sharma, Madhusudhanarao Katiki, Pramod Kumar, Bhola R. Gurjar, Shailly Tomar, Ashwani K. Sharma, Pravindra Kumar.

Journal Name: Protein & Peptide Letters

Volume 24 , Issue 3 , 2017

Graphical Abstract:


Abstract:

Globulins are a major class of seed storage proteins which were thought to be enzymatically inactive. These proteins belong to the most ancient cupin superfamily. They can be graded into 11S legumin type and 7S vicilin type based on their sedimentation coefficients. Members from both classes share structural homology are thought to have evolved from either one-domain germin predecessor by duplication or by horizontal gene transfer of two-domain gene from bacteria to eukaryotes. Globulins are known to define the nutritional quality of the seeds, however, they are also involved in sucrose binding, desiccation, defense against microbes, hormone binding and oxidative stress etc. Major drawback with globulins is their tendency to bind to IgE. Studying structural-functional behavior of such protein can help in modifying proteins for enhanced functionality in food processing industries.

Keywords: Globulins, cupin superfamily, 7S vicilin, 11S legumin, evolution, seed storage protein.

Rights & PermissionsPrintExport Cite as

Article Details

VOLUME: 24
ISSUE: 3
Year: 2017
Page: [267 - 277]
Pages: 11
DOI: 10.2174/0929866523666161220112641
Price: $58

Article Metrics

PDF: 13
HTML: 1