Recent Trends in Nanotechnology-Based Drugs and Formulations for Targeted Therapeutic Delivery

Author(s): Hafiz M. N. Iqbal*, Angel M.V. Rodriguez*, Rekha Khandia*, Ashok Munjal*, Kuldeep Dhama*.

Journal Name: Recent Patents on Inflammation & Allergy Drug Discovery

Volume 10 , Issue 2 , 2016

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Abstract:

Background: In the recent past, a wider spectrum of nanotechnologybased drugs or drug-loaded devices and systems has been engineered and investigated with high interests.

Objective: The key objective is to help for an enhanced/better quality of patient life in a secure way by avoiding/limiting drug abuse, or severe adverse effects of some in practice traditional therapies.

Method: Various methodological approaches including in vitro, in vivo, and ex vivo techniques have been exploited, so far. Among them, nanoparticles-based therapeutic agents are of supreme interests for an enhanced and efficient delivery in the current biomedical sector of the modern world.

Results: The development of new types of novel, effective and highly reliable therapeutic drug delivery system (DDS) for multipurpose applications is essential and a core demand to tackle many human health related diseases. In this context, nanotechnology-based several advanced DDS have been engineered with novel characteristics for biomedical, pharmaceutical and cosmeceutical applications that include but not limited to the enhanced/improved bioactivity, bioavailability, drug efficacy, targeted delivery, and therapeutically safer with an extra advantage of overcoming demerits of traditional drug formulations/designs. This review work is focused on recent trends/advances in nanotechnology-based drugs and formulations designed for targeted therapeutic delivery. Moreover, information is also reviewed and given from recent patents and summarized or illustrated diagrammatically to depict a better understanding. Recent patents covering various nanotechnology-based approaches for several applications have also been reviewed.

Conclusion: The drug-loaded nanoparticles are among versatile candidates with multifunctional characteristics for potential applications in biomedical, and tissue engineering sector.

Keywords: Biomaterials, biomedical sector, drug delivery, drug-loaded nanoparticles, nanotechnology, therapeutic approaches.

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Article Details

VOLUME: 10
ISSUE: 2
Year: 2016
Page: [86 - 93]
Pages: 8
DOI: 10.2174/1872213X10666161213162823

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