Macrogols: A Misleading Cause of Drug Hypersensitivity Diagnosis

Author(s): Gianfranco Calogiuri* , Caterina Foti , Maria Beatrice Bilo , Lene Heise Garvey .

Journal Name: Clinical Immunology, Endocrine & Metabolic Drugs (Discontinued)

Volume 4 , Issue 1 , 2017

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Abstract:

Background: Polyethylene Glycols (PEGs) or macrogols are reputed to be inert and nonimmunogenic substances, however they are reported to induce immediate type hypersensitivity reactions. Due to their widespread use in extensively consumed products as cosmetics and drugs, the attention towards these substances is still low.

Conclusion: Therefore, it may be useful to focus clinician's attention on possible adverse reactions caused by these polymers.

Keywords: Anaphylaxis, excipients, hypersensitivity, immediate-type reaction, macrogols, polyethylene glycols.

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Article Details

VOLUME: 4
ISSUE: 1
Year: 2017
Page: [9 - 13]
Pages: 5
DOI: 10.2174/2212707004666161209161535
Price: $58

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