Abstract
Risk reduction and the attainment of good outcomes in contemporary cataract surgery depend in part on patient compliance with a postoperative regimen of topical eye drops. Topical drops are expensive and challenging to instill properly for patients. The consequences of noncompliance or poor compliance can be significant for the patient (in the case of a complication) and for society (in the case of development of antibiotic resistance). For all of these reasons, new approaches that reduce the need for topical therapy are beginning to emerge, including intracameral injection, sustained or slow-release drug delivery mechanisms, and the recently introduced “Dropless cataract surgery,” which involves intravitreal injection of single-use, compounded combination of antibiotics and corticosteroids. This paper is a review of the rationale for reducing topical therapy in cataract surgery prophylaxis, and what is known to date about the efficacy and safety of the dropless approach.
Keywords: Cataract surgery, antibiotic prophylaxis, endophthalmitis, intracameral, intravitreal, corticosteroid, compliance, transzonular injection.
Current Pharmaceutical Design
Title:Dropless Cataract Surgery: An Overview
Volume: 23 Issue: 4
Author(s): Richard L. Lindstrom, M. Stewart Galloway, Andrzej Grzybowski and Jeffrey T. Liegner
Affiliation:
Keywords: Cataract surgery, antibiotic prophylaxis, endophthalmitis, intracameral, intravitreal, corticosteroid, compliance, transzonular injection.
Abstract: Risk reduction and the attainment of good outcomes in contemporary cataract surgery depend in part on patient compliance with a postoperative regimen of topical eye drops. Topical drops are expensive and challenging to instill properly for patients. The consequences of noncompliance or poor compliance can be significant for the patient (in the case of a complication) and for society (in the case of development of antibiotic resistance). For all of these reasons, new approaches that reduce the need for topical therapy are beginning to emerge, including intracameral injection, sustained or slow-release drug delivery mechanisms, and the recently introduced “Dropless cataract surgery,” which involves intravitreal injection of single-use, compounded combination of antibiotics and corticosteroids. This paper is a review of the rationale for reducing topical therapy in cataract surgery prophylaxis, and what is known to date about the efficacy and safety of the dropless approach.
Export Options
About this article
Cite this article as:
Lindstrom L. Richard, Galloway Stewart M., Grzybowski Andrzej and Liegner T. Jeffrey, Dropless Cataract Surgery: An Overview, Current Pharmaceutical Design 2017; 23 (4) . https://dx.doi.org/10.2174/1381612822666161129150628
DOI https://dx.doi.org/10.2174/1381612822666161129150628 |
Print ISSN 1381-6128 |
Publisher Name Bentham Science Publisher |
Online ISSN 1873-4286 |
- Author Guidelines
- Graphical Abstracts
- Fabricating and Stating False Information
- Research Misconduct
- Post Publication Discussions and Corrections
- Publishing Ethics and Rectitude
- Increase Visibility of Your Article
- Archiving Policies
- Peer Review Workflow
- Order Your Article Before Print
- Promote Your Article
- Manuscript Transfer Facility
- Editorial Policies
- Allegations from Whistleblowers
- Announcements
Related Articles
-
The Genetic Landscapes of Inflammation-Driven Gastrointestinal Tract Cancers
Current Pharmaceutical Design Genetics and Gene Therapy of Anderson-Fabry Disease
Current Gene Therapy New Anti-Angiogenic Targeted Therapy in Advanced Renal Cell Carcinoma (RCC):Current Status and Future Prospects
Reviews on Recent Clinical Trials Design of Combretastatin A-4 Analogs as Tubulin Targeted Vascular Disrupting Agent with Special Emphasis on Their Cis-Restricted Isomers
Current Pharmaceutical Design Behavioral Experimental Paradigms for the Evaluation of Drug’s Influence on Cognitive Functions: Interpretation of Associative, Spatial/Nonspatial and Working Memory
CNS & Neurological Disorders - Drug Targets Pulmonary Circulation and Pulmonary Function in Neonatal Lung Hypoplasia:Treatment with Corticosteroids
Current Pediatric Reviews Neopterin as a Marker for Immune System Activation
Current Drug Metabolism Regulation of TAK / P-TEFb in CD4+ T Lymphocytes and Macrophages
Current HIV Research The MRP Family and Anticancer Drug Metabolism
Current Drug Metabolism Indoleamine 2,3-Dioxygenase in Hematopoietic Stem Cell Transplantation
Current Drug Metabolism EGFR High Expression, but not KRAS Status, Predicts Sensitivity of Pancreatic Cancer Cells to Nimotuzumab Treatment In Vivo
Current Cancer Drug Targets Nanotechnology Allied to Nitric Oxide Release Materials for Dermatological Applications
Current Nanoscience How Do Dendritic Cells Play the Role in Ischemia/Reperfusion Triggered Kidney Allograft Rejection
Current Gene Therapy Nanocrystals of Glycyrrhetinic Acid: Comparative Efficiency of Particle Size Reduction Techniques
Drug Delivery Letters Hematopoietic Progenitor and Stem Cells Circulate by Surfing on Intracellular Ca2+ Waves: A Novel Target for Cell-based Therapy and Anti-cancer Treatment?
Current Signal Transduction Therapy Analysis of Nickel-Binding Peptides in a Human Hepidermoid Cancer Cell Line by Ni-NTA Affinity Chromatography and Mass Spectrometry
Protein & Peptide Letters The Metabolism of Methazolamide in Immortalized Human Keratinocytes, HaCaT Cells
Drug Metabolism Letters Synthesis, Structure and Antibacterial Evaluation of Some N-substituted 3-amino-5-hydroxy-4-phenyl-1H-pyrazole-1-carboxamides
Medicinal Chemistry Novel Antiplatelet Therapy in Acute Coronary Syndromes: What is New in the Pipeline?
Current Vascular Pharmacology Poly(lactide-co-glycolide)-based Micro and Nanoparticles for the Controlled Drug Delivery of Vitamins
Current Nanoscience