Current Technologies To Increase The Transdermal Delivery Of Drugs

Volume: 2

Physical Penetration Enhancers: Therapeutic Applications and Devices

This volume covers the methods of using skin penetrating agents, the therapeutic applications of physical penetration enhancers and devices in the market. Chapters cover topics such as transdermal ...
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Microneedles

Pp. 210-259 (50)

Yunhua Gao, Yuqin Qiu and Suohui Zhang

Abstract

Transdermal drug delivery is a well-accepted route of administration for therapeutical drugs. Skin is the largest area human body organ, however, the substantial barrier property of the skin stratum corneum limits practical value of transdermal route of drug administration. It has been proved that microneedle array devices can overcome the barrier characteristics of the stratum corneum and enhance the delivery of therapeutic medicines through skin. This chapter focuses on looking at the microneedle-mediated transdermal drug delivery for therapeutical applications. The definition of microneedles, enhancement mechanisms and devices in research or in the market are also depicted.

Keywords:

Definition, Devices in research or in the market, Mechanisims of action, Microneedle, Therapeutical applications.

Affiliation:

Technical Institute of Physics and Chemistry, Chinese Academy of Sciences, Beijing, 100190, China.