Novel Chromeno[2,3-d]pyrimidines-Design, Synthesis and Antioxidant Activity

Title:Novel Chromeno[2,3-d]pyrimidines-Design, Synthesis and Antioxidant Activity

Volume: 14 Issue: 7

Author(s): Kotiah Yalagala, Sreekantha B. Jonnalagadda*, Suresh Maddila, Surjyakanta Rana and Surya Narayana Maddila

Affiliation:

• School of Chemistry & Physics, University of KwaZulu-Natal, Westville Campus, Chiltern Hills, Durban-4000,south africa

Keywords: Pyrimidines, synthesis, anti-oxidant activity, simple method, in vitro studies, human body.

Abstract: Introduction: Fourteen novel 8,8-dimethyl-8,9-dihydro-5H-chromeno[2,3-d]pyrimidin-6(7H)- one derivatives were rationally designed and synthesized successfully. The synthetic procedures adopted for the target molecules were achieved by facile protocols and the yields were good to excellent (> 80%).

Cite this article as:

Yalagala Kotiah, Jonnalagadda B. Sreekantha*, Maddila Suresh, Rana Surjyakanta and Maddila Narayana Surya, Novel Chromeno[2,3-d]pyrimidines-Design, Synthesis and Antioxidant Activity, Letters in Drug Design & Discovery 2017; 14 (7) . https://dx.doi.org/10.2174/1570180814666161123143637