Background: Neisseria are usually harmless inhabitants of otherwise
asymptomatic persons’ upper respiratory mucosal surfaces.
Method: It is, therefore, expected that a disturbance in the physiology leads to nongonococcal,
non-meningococcal Neisseria becoming pathogenic.
Result: We report the case of a diabetic man who initially presented with nonspecific
symptoms and was later found to have cystitis caused by N. oralis.
Conclusion: We also review the pertinent literature and discuss available evidence
on pathophysiological mechanisms of infection with such commensal bacteria.