Synthesis and Evaluation of Anti-Tuberculosis and Anti-Cancer Activities of Hydrazones and N-Acylhydrazones by Using Sonochemistry, A New General Procedure

Title:Synthesis and Evaluation of Anti-Tuberculosis and Anti-Cancer Activities of Hydrazones and N-Acylhydrazones by Using Sonochemistry, A New General Procedure

Volume: 14 Issue: 6

Author(s): Ligia Souza da Silveira Pinto, Marcus V. N. de Souza*Carlos R. Kaiser

Affiliation:

• Instituto de Tecnologia em Fármacos-Far-Manguinhos, FioCruz-Fundação Oswaldo Cruz, P.O. Box: 21041- 250, Rio de Janeiro,Brazil

Keywords: Hydrazones, N-acylhydrazones, sonochemistry, anti-tuberculosis and anti-cancer activities, drug discovery.

Abstract: Background: In continuation of our research on sonochemistry and due to the importance and application of hydrazones and N-acylhydrazones in drug discovery, in this work we report a new general and efficient synthesis of these classes with different aromatic and heteroaromatic nucleus assisted by ultrasound and their respective anti-tuberculosis and anti-cancer activities.

Cite this article as:

da Silveira Pinto Souza Ligia, de Souza V. N. Marcus*, Kaiser R. Carlos, Synthesis and Evaluation of Anti-Tuberculosis and Anti-Cancer Activities of Hydrazones and N-Acylhydrazones by Using Sonochemistry, A New General Procedure, Letters in Drug Design & Discovery 2017; 14 (6) . https://dx.doi.org/10.2174/1570180814666161121120414