Calcium phosphate materials (CPM) are widely used in dentistry and maxillofacial surgery.
The presence of microbial biofilms and external infections is responsible for the failure of many procedures
of dental implants and bone grafts. In an attempt to reduce the percentage of these infectious
processes antibiotics have been associated with CPM improving certain conditions. For instance, antibiotics
administered orally or intravenously have less effect and the blood flow in relation to this is poor
near implants and grafts. Tissue engineering (TE) has employed CPM as a local drug delivery vehicle to
be more effective and efficient in bone infections. This review is presented to describe current antibiotics
used and the physical and chemical properties of scaffolds.
Keywords: Antibiotics, bone infections, calcium phosphate materials, dentistry, drug delivery, maxillofacial surgery, tissue
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