Lipase Immobilization on Siliceous Supports: Application to Synthetic Reactions

Author(s): Diego Cazaban, Lorena Wilson, Lorena Betancor.

Journal Name: Current Organic Chemistry

Volume 21 , Issue 2 , 2017

Submit Manuscript
Submit Proposal

Graphical Abstract:


Abstract:

In the last quarter century, immobilization of lipases has rapidly grown into a field of converging knowledge on material science, chemical engineering, biochemistry, etc. The majority of the cumulative work on lipase immobilization has been done on silica (Si) based supports. Researchers have investigated the effect of different Si architectures such as monolith, particles and aerogels on the properties of the immobilized lipase. These heterogenous catalysts have proved efficient in synthetic reactions such as biodiesel formation, where, unlike other supports, siliceous materials are able to resist nonaqueous media, providing stability and reusability. The use of numerous sources of this type of enzymes assures the universality of silica for lipase immobilization. This work summarizes the immobilization strategies and functionalization methods on siliceous materials that have provided a fundamental technology base to exploit the power of lipases as biocatalyts.

Keywords: Biocatalysis, biodiesel production, enzyme immobilization, lipase, silica, siliceous materials.

Rights & PermissionsPrintExport Cite as


Article Details

VOLUME: 21
ISSUE: 2
Year: 2017
Page: [96 - 103]
Pages: 8
DOI: 10.2174/1385272821666161108103040
Price: $58

Article Metrics

PDF: 20
HTML: 3
EPUB: 1
PRC: 1