Review of Characteristics, Pharmacology, Determination and Pharmacokinetics of Rhaponticin

Author(s): Yang Sun, Xuhua Liang, Hua Cheng, Wanqiang Wang, Xiangsheng Jiang, Ping He, Yingyong Zhao, Junjun Wu.

Journal Name: Mini-Reviews in Organic Chemistry

Volume 14 , Issue 1 , 2017

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Abstract:

Rhaponticin (RHA) is a stilbene glucoside compound that can be found in medicinal plant of Rheum L. RHA has been reported to possess several biological effects including antitumor, antithrombotic, antioxidant, vasorelaxant, defense for gastritis activities. It also shows beneficial activities on diabetic mice. According to reported literatures, an overview of spectroscopy characteristics, pharmacological activity, content determination and pharmacokinetics, etc. for RHA has been presented. Moreover, this work provides a certain reference value for developing the therapeutic drug of RHA.

Keywords: Rhaponticin, stilbene glucoside, anti-diabetic activity, structural characteristics of RHA, anti-oxidation activity, anti-allergic activity.

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Article Details

VOLUME: 14
ISSUE: 1
Year: 2017
Page: [24 - 34]
Pages: 11
DOI: 10.2174/1570193X13666161102152403
Price: $58

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