Core-shell Semiconductor Nanocrystals: Effect of Composition, Size, Surface Coatings on their Optical Properties, Toxicity and Pharmacokinetics

Author(s): Wafa' T. Al-Jamal.

Journal Name: Current Pharmaceutical Design

Volume 23 , Issue 3 , 2017

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Abstract:

Quantum dots are semiconducting nanocrystals that exhibit extraordinary optical properties. QD have shown higher photostability compared to standard organic dye type probes. Therefore, they have been heavily explored in the biomedical field. This review will discuss the different approaches to synthesis, solubilise and functionalise QD. Their main biomedical applications in imaging and photodynamic therapy will be highlighted. Finally, QD biodistribution profile and in vivo toxicity will be discussed.

Keywords: Quantum dots, fluorescence, imaging, therapy, theranostic.

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Article Details

VOLUME: 23
ISSUE: 3
Year: 2017
Page: [340 - 349]
Pages: 10
DOI: 10.2174/1381612822666161026164920
Price: $58

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