Background: New anticancer drug discovery, development and manufacture
entered the bottleneck stage. Many limitations of both technology and animal models slow
down the anticancer drug developments
Objective: To ease economic burdens for drug developers and general patient populations.
Methods: Key factors affecting anticancer drug developments and possible roadmaps for
updating drug screening routines worldwide are suggested.
Results: Drug development chains must be updated and better drug development paradigms
must be established.
Conclusions: This world welcomes global participations in anticancer drug developments
Keywords: Anticancer drug development, neoplasm metastasis, cost-effective, medicinal chemistry,
animal models, drug toxicity, cancer stem cells, individualized cancer therapy.
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