Methods for Selecting Phage Display Antibody Libraries

Author(s): Ricardo Jara-Acevedo , Paula Diez , Maria Gonzalez-Gonzalez , Rosa Maria Degano , Nieves Ibarrola , Rafael Gongora , Alberto Orfao , Manuel Fuentes .

Journal Name: Current Pharmaceutical Design

Volume 22 , Issue 43 , 2016

Abstract:

The selection process aims sequential enrichment of phage antibody display library in clones that recognize the target of interest or antigen as the library undergoes successive rounds of selection. In this review, selection methods most commonly used for phage display antibody libraries have been comprehensively described.

Keywords: Phage display, antibody, antigen, epitope.

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Article Details

VOLUME: 22
ISSUE: 43
Year: 2016
Page: [6490 - 6499]
Pages: 10
DOI: 10.2174/1381612822666161007153127
Price: $58

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