Synthesis and Nematocidal Activity of Novel Pyrazole Carboxamide Derivatives Against Meloidogyne incognita

Author(s): Wen Zhao, Zhong-Hua Shen, Jia-Hua Xing, Tian-Ming Xu, Wei-Li Peng, Xing-Hai Liu.

Journal Name: Letters in Drug Design & Discovery

Volume 14 , Issue 3 , 2017

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Abstract:

Background: A series of novel 2,6-dichloro-4-(trifluoromethyl)phenyl)-3-(trifluoromethyl) - 1H-pyrazole-4-carboxamide derivatives were designed and synthesized.

Method: All the title compounds were confirmed by 1H NMR and MS.

Results: The primarily nematicidal activity results indicated that some of them exhibited moderate control efficacy against the tomato root-knot nematode disease caused by Meloidogyne incognita.

Keywords: Synthesis, trifluoromethylpyrazole, nematocidal activity, Meloidogyne incognita.

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Article Details

VOLUME: 14
ISSUE: 3
Year: 2017
Page: [323 - 329]
Pages: 7
DOI: 10.2174/1570180813666160930164327
Price: $58

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