Background: Tuberculosis caused by Mycobacterium tuberculosis
(MTB) is currently a major health concern due to its growing mortality rates around
the world. The known anti-TB drugs although are available for the treatment but it
produces adverse side effects on the human health and are also not very cost effective.
Moreover, emergence of multidrug resistance (MDR) phenomenon has also
compromised their activities.
Objective: Hence there is an urgent need to search novel drugs and compounds from
natural sources having lesser side effects which have proved to be vital and widely
used nowadays. Many recent studies have been established which show promising
antimycobacterial activities against MTB.
Result: This review summarizes the various naturally occurring active compounds acting on different
targets against MTB. Moreover, it also deals with the compounds having patent perspective.
Conclusion: Together, the article laid emphasis on reverting towards the natural compounds so that further
work is carried out to exploit their therapeutic interventions.