Exercise and Peripheral Arterial Disease
Pp. 190-200 (11)
Peripheral artery disease (PAD) is a disease of the lower extremities that is a
component of the chronic, progressive atherosclerotic process. In the United States,
there are 8 million adults with PAD. Aside from the increased risk of cardiovascular
morbidity and mortality, it leads to altered skeletal muscle energetics linked to
mitochondrial dysfunction that hastens physical decline and disability. Fortunately,
exercise medicine benefits clients with PAD by increasing walking time, walking
distance, and functional capacity that reduces the risk of cardiovascular events while
improving quality of life. The benefits of exercise medicine in PAD are linked to the
enhanced distal blood flow and O2 supply due to vascular adaptations.
Atherosclerosis, Atrophy, Cardiovascular events, Diabetes, Exercise
medicine, Mitochondrial dysfunction, Muscle energetic, Peripheral artery disease.
American Society of Exercise Physiologists, USA.