Cranberry for Urinary Tract Infection: From Bench to Bedside

Author(s): Seyed Fazel Nabavi, Antoni Sureda, Maria Daglia, Morteza Izadi, Seyed Mohammad Nabavi.

Journal Name: Current Topics in Medicinal Chemistry

Volume 17 , Issue 3 , 2017

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Abstract:

Urinary tract infections are common infectious diseases which can occur in any part of the urinary tract such as bladder, kidney, ureters, and urethra. They are commonly caused by bacteria that enter through the urethra. Urinary tract infections commonly develop in the bladder and spread to renal tissues. Up to now, there are different antimicrobial agents which have beneficial role on urinary tract infections. However, most of them cause different adverse effects and therefore, much attention has been paid to the search for effective therapeutic agents with negligible adverse effects. Cranberry is known as one of the most important edible plants, which possesses potent antimicrobial effects against the bacteria responsible for urinary tract infections. Growing evidence has shown that cranberry suppresses urinary tract infections and eradicates the bacteria. Therefore, the aim of this study is to critically review the available literature regarding the antimicrobial activities of cranberry against urinary tract infection microorganisms. In addition, we discuss etiology, epidemiology, risk factors, and current drugs of urinary tract infections to provide a more complete picture of this disease.

Keywords: Cranberry, Urinary tract infection, Antibiotics, Antimicrobial effect, Escherichia coli.

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Article Details

VOLUME: 17
ISSUE: 3
Year: 2017
Page: [331 - 339]
Pages: 9
DOI: 10.2174/1568026616666160829161031
Price: $58

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